Metabolic Pathway Research · GLP-1 / glucagon receptor agonist

PemvidutideBalanced GLP-1/glucagon receptor agonist peptide.

A dual GLP-1/glucagon receptor agonist studied in hepatic and metabolic pathway research.

Also known as ALT-801; MD-1373; SP-1373. CAS No. 2538014-94-5.

3 papers·Clinical development·COA Unverified·0 saved

Scientific name

Balanced GLP-1/glucagon receptor agonist peptide.

CAS No.

2538014-94-5

Scientific Details

Quick Facts

GLP-1 receptor and glucagon receptor

Altimmune

Mechanism of Action

GLP-1 receptor agonism

Glucagon receptor agonism

Liver fat metabolism

Key Pathways

Incretin signaling

Hepatic lipid metabolism

Scientific Research

Year	Title / Journal	Type	Cites
2025	Noureddin 2025 — Pemvidutide Phase 2 MASH Trial The Lancet	RCT	16
2025	Harrison 2025 - Pemvidutide in MASLD: Randomized Phase 2 Trial Journal of Hepatology	RCT	140
2022	Nestor 2022 - ALT-801 GLP-1/Glucagon Dual Agonist in NASH Models Communications Biology	Preclinical	53

Showing 3 of 3 papers

Regulatory Status

USResearch only

EUNot approved

UKResearch only

AUResearch only

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