Barnhart 2011 — Adipotide in Obese Monkeys

Science Translational Medicine·November 9, 2011

K. F. Barnhart, et al.

Summary

Adipotide targeted white-fat vasculature, causing weight loss and improved insulin resistance in obese monkeys.

Study Details

Study Design

Nonhuman primate preclinical study

Indication

Obesity and insulin resistance

Intervention

Adipotide peptidomimetic CKGGRAKDC-GG-D(KLAKLAK)2

Species

Animal

Risk of Bias Assessment

Preclinical primate data; safety/translation uncertain