Chang 2011 — BPC-157 Promotes Tendon Fibroblast Outgrowth and Migration

Journal of Applied Physiology·January 1, 2011

Cheng-Hao Chang, et al.

Summary

This mechanistic paper found BPC-157 promoted tendon fibroblast outgrowth, migration, and FAK-paxillin pathway activation, strengthening the biological plausibility for tendon repair effects.

Study Details

Study Design

In vitro tendon fibroblast and ex vivo tendon outgrowth study

Indication

Tendon healing mechanisms

Intervention

BPC-157 pentadecapeptide

Species

Cell

Risk of Bias Assessment

Preclinical mechanistic study