Mahlapuu 2021 - HEAL LL-37 Phase IIb Trial in Venous Leg Ulcers

Wound Repair and Regeneration·October 1, 2021

M. Mahlapuu

Summary

HEAL LL-37 evaluated efficacy and safety of LL-37 in hard-to-heal venous leg ulcers, adding later-stage clinical evidence to the LL-37 wound-healing literature.

Study Details

Study Design

Phase IIb double-blind randomized placebo-controlled trial

Indication

Hard-to-heal venous leg ulcers

Intervention

Topical LL-37 cream vs placebo

Species

Human

Risk of Bias Assessment

Phase IIb wound trial