Sarafraz-Yazdi 2022 — PNC-27 Binds HDM-2 on Cancer Cell Membranes

Cancers

E. Sarafraz-Yazdi, et al.

Summary

PNC-27 was reported to bind membrane HDM-2 and kill cancer cells via pore-forming / membranolytic mechanisms.

Study Details

Study Design

Preclinical mechanistic study

Indication

Cancer membrane HDM-2 targeting

Intervention

PNC-27 peptide

Species

Cell

Risk of Bias Assessment

Preclinical only