Sarafraz-Yazdi 2010 - PNC-27 Anticancer Peptide Binds MDM2 and Induces Cancer Cell Necrosis

Cancer Research·January 1, 2010

E. Sarafraz-Yazdi, M. D. Bowne, M. Warso

Summary

PNC-27 is an experimental p53-derived peptide studied for selective cancer-cell membrane disruption via MDM2-related mechanisms.

Study Details

Study Design

Cell and xenograft anticancer mechanism study

Indication

Cancer cell membrane MDM2 targeting

Intervention

PNC-27 peptide

Species

Cell

Risk of Bias Assessment

Preclinical; no established human efficacy