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Sermorelin Research

Growth hormone-releasing hormone antagonists induce autophagy in cancer cells

Growth Horm IGF Res·October 9, 2025

Madan Sigdel, Saikat Fakir, Md Matiur Rahman Sarker, Nektarios Barabutis

Summary

GHRH antagonist JV-1-36 elevated autophagy-related proteins (ATG-5, ATG-3, ATG-7, ATG-16L1) in GHRH receptor-expressing cancer cells (MDA-MB-468, A549).

Study Details
Study Design

In vitro experimental study

Indication

Cancer (breast and lung)

Intervention

GHRH antagonist JV-1-36

Species

Cell

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Evidence QualityN/A
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