Maio 2010 — Thymosin Alpha-1 in Melanoma

J Clin Oncol·April 1, 2010

Michele Maio, Andrzej Mackiewicz, Alessandro Testori, Uwe Trefzer, Virginia Ferraresi, et al., Francesco Cognetti

Summary

Results suggest Tα1 has activity in patients with metastatic melanoma. Provides rationale for further clinical evaluation of this immunomodulatory agent.

Study Details

Study Design

Large randomized multicenter trial with 5 treatment arms

Indication

Metastatic melanoma

Intervention

Thymosin alpha-1 + DTIC

Species

Human

Sample Size

488 subjects