Ruff 2010 — Thymosin Beta-4 Phase 1 Study in Healthy Adults

Annals of the New York Academy of Sciences·June 1, 2010

D. Ruff, R. Crockford, P. Girardi, et al.

Summary

This phase 1 trial evaluated safety and tolerability of synthetic thymosin beta-4 as part of development for potential myocardial injury applications.

Study Details

Study Design

Randomized placebo-controlled single- and multiple-dose phase 1 study

Indication

Safety and tolerability before acute myocardial infarction development program

Intervention

Synthetic thymosin beta-4 vs placebo

Species

Human

Sample Size

40 subjects

Risk of Bias Assessment

Phase 1 safety study; not efficacy