Vasireddi 2025 — BPC-157 Systematic Review

HSS J·July 31, 2025

Nikhil Vasireddi, Henrik Hahamyan, Michael J. Salata, Michael Karns, Jacob G. Calcei, James E. Voos, John M. Apostolakos

Summary

36 articles included: 21 on mechanism of action, 15 on musculoskeletal outcomes, 3 on metabolism, 4 on safety. Only 1 clinical study identified. No high-quality human clinical evidence.

Study Details

Study Design

Systematic review per PRISMA guidelines

Indication

Musculoskeletal

Sample Size

36 subjects

Risk of Bias Assessment

Independent systematic review